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Thai) 1:
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Objective: To evaluate antibacterial activity of the Indonesian water soluble green tea extract, Camellia sinensis, against clinical isolates of methicillin-resistant Staphylococcus aureus(S. aureus) (MRSA) and multi-drug resistant Pseudomonas aeruginosa (MDR-P. aeruginosa). Methods: Antimicrobial activity of green tea extract was determined by method and the minimum inhibitory concentration (MIC) was determined by ththee dtiwsocf odlidf fsuesriioanl mbruoltthi- ddirluugti orenssi smtaentth coldin. iTchael itseosltaetdes boafc Ste. raiau rueusisn agn din P t.h aise rsutguidnyo swae, roeb ttahien esdta fnrdomar dL asbtroariantos rayn odf Clinical Microbiology, Faculty of Medicine, University of Indonesia. Results: The results showed that the inhibition zone diameter of green tea extracts for S. aureusAinThCibCi ti2o5n9 2z3o naen dd iaMmReStAer wfoerr Pe .( 1a8e.r9u7g0i依n0o.s2a8 7A) TmCmC ,2 7a8n5d3 a(1n9d.1 M30D依R0.-2P50. ) amermug rinesopsae cwtievreel (y1.7 .W55h0i依le0. 3t9h3e) mm and (17.670依0.398) mm respectively. The MIC of green tea extracts against S. aureus ATCC 25923 and MRSA were 400 μg/mL and 400 μg/mL, respectively, whereas the MIC for P. aeruginosa ATCC 27853 and MDR-P. aeruginosa were 800 μg/mL, and 800 μg/mL, respectively. Conclusions: Camellia sinensis leaves extract could be useful in combating emerging drug- resistance caused by MRSA and P. aeruginosa.
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