Results
The relative expression of the genes COL1A1, COL1A2, COL3A1
and COL5A1 presented wide variation among the individuals
with traumatic anterior shoulder instability. Both increased
and decreased collagen gene expression in the anteroinferior
region, in relation to the anterosuperior region, was
observed (Fig. 1). The expression of COL1A1, COL1A2 and
COL3A1 did not differ significantly between the AI and AS
regions (Table 1). However, the AI region presented reduced
expression of COL5A1 in relation of the AS region of the
glenohumeral capsule of patients with shoulder instability
(p = 0.028; r =
−0.3665; Table 1).
No correlation between the levels of collagen gene expression
and the age at which the patient was affected, the age at
the time of surgery or the time that had elapsed from the first
dislocation to sample collection was observed in either of the
regions studied (p > 0.05 for all the analyses).