Results (
Indonesian) 1:
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Surgical consultation should be obtained on all patients withcomplicated CDI. Surgical therapy should be considered in patients with any one of the following attributed to CDI: hypotension requiring vasopressor therapy; clinical signs of sepsis and organ dysfunction; mental status changes; WBC count ≥ 50,000 cells/ μ l, lactate ≥ 5 mmol / l; or complicated CDI with failure to improve on medical therapy aft er 5 days. (Strong recommendation, moderate-quality evidence)A major challenge in the management of severe, complicated CDI is the inability to predict in which patient medical therapy will fail, and lack of consensus on the indications or timing of surgery except the very rare complication of colonic perforation. Th e vague term “ clinical deterioration ” is frequently mentioned in already critically ill patients in whommedical therapy has failed. Th ese strategies rely on surgery as a salvage therapy, which may account for the poor outcomes associated with subtotal colectomy in complicated CDI, and mortality rates that range from 35 % to 80 % ( 38,39,41,42,65,72 ).
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