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Sorption calorimetry is less commonly used in routine characterizationof drug substances and raw materials. In contrast,automated water sorption equipment is a standard techniquethat requires minimal sample preparation and effort,making itmore appropriate for routine characterization. The main dataobtained by the water sorption technique is water weight versusRH. Although it is necessary to quantify the water contentof materials and the isotherm provides practical value in characterizingtheir “hygroscopicity
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