Evidence based medicine (EBM) is the conscientious, explicit, and judicious use of current best evidence in making decisions about the care of individual patients [28]. The goal of evidence-based medicine is to complement the existing clinical decision making processes with the best available research evidence and patient values. Furthermore, EBM provides a direction and rationale for clinicians to manage their patients, and a means to integrate clinical expertise with the best available research evidence. It has been mainly used in the evaluation of clinical therapy effectiveness, especially due to the success of Randomized Controlled Trials (