The net benefit of intraoperative prevention in
the base case analysis was estimated with uncertainty
in model inputs. We, therefore, conducted
probabilistic sensitivity analysis by sampling 10,000
random input values from the input distributions
specified in Table II. We then performed the costeffectiveness
analysis 10,000 times with the random
input values to estimate the probability that the
intraoperative prevention strategy would be cost
effective (ie, the frequency that intraoperative prevention
would yield positive net benefits among
the probabilistic samples).