Postoperative pain management is based on a number of principles. Pain prevention is
preferable to, and more efficacious than, treatment of established pain15. Multimodal
analgesia is a rational approach to pain management and is more effective. The aim of
multimodal analgesia combinations is to reduce postoperative pain. Theoretically,
multimodal analgesia is achieved by a combination of opioids, and regional blocks, which
attenuate the pain-related signals in the central nervous system, and nonsteroidal antiinflammatory
drugs, which act mainly in the periphery to inhibit the initiation of pain
signals.