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After reviewing some of the above mentioned theories, we can conclude that pain is adynamic phenomenon; all the nociceptive signals will be modulated at all levels from theperiphery to the brain but we still have to take into account genetic and environmentalfactors that will influence the acute perception and the development of persistent pain.Understanding the neurophysiologic mechanisms involved in the development andmaintenance of pain will help the clinician to devise a more effective treatment plan.
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