Results (
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For living kidney donors, the date of cohort entry was the date of nephrectomy; for nondonors, it was randomly assigned (simulated nephrectomy date) to establish the date that follow-up began. Percentages may not total 100 because of rounding. IQR denotes interquartile range. † P values were derived from generalized linear models with generalized estimating equations for the correlation structure. A normal distribution was specified when the variable was continuous, a Poisson distribution when the variable was a count, a multinomial distribution when the variable was categorical, and a binomial distribution when the variable was binary. ‡ To comply with privacy regulations for minimizing the chance of identification of a study participant, numbers of participants are suppressed in the case of 5 or fewer participants (reported as ≤5). § Income was categorized according to fifths of average neighborhood income, with the first quintile calculated as the lowest income and the fifth quintile as the highest income. This was done only for urban residents (96% of the cohort), since it was problematic to delineate neighborhood boundaries in rural areas. ¶ Ontario health care database records were available from July 1991. In this study, baseline records were available starting at the age of 25 years for 89% of women and starting at the age of 20 years for 61% of women. ‖ This analysis was restricted to women with at least one previous pregnancy. ** As expected, donors had more visits to primary care physicians in the year before the cohort-entry date than nondonors because such visits are a necessary part of the donor evaluation process.
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