TREATMENTACUTE GOUTY ARTHRITIS(Fig. 1-1)Nonpharmacologic Therapy• Pati translation - TREATMENTACUTE GOUTY ARTHRITIS(Fig. 1-1)Nonpharmacologic Therapy• Pati Indonesian how to say

TREATMENTACUTE GOUTY ARTHRITIS(Fig.

TREATMENT
ACUTE GOUTY ARTHRITIS
(Fig. 1-1)
Nonpharmacologic Therapy
• Patients may be advised to reduce their intake of foods high in purines (e.g.,
organ meats), avoid alcohol, increase fluid intake, and lose weight if obese.
• Joint rest for 1 to 2 days should be encouraged, and local application of ice
may be beneficial.
Nonsteroidal Antiinflammatory Drugs
• Nonsteroidal antiinflammatory drugs (NSAIDs) are the mainstay of therapy
because of their excellent efficacy and minimal toxicity with shortterm
use. There is little evidence to support one NSAID as more efficacious
than another, and three drugs (indomethacin, naproxen, and sulindac)
have FDA approval for this indication (Table 1-1).
• Therapy should be initiated with maximum recommended doses for gout
at the onset of symptoms and continued for 24 hours after complete
resolution of an acute attack, then tapered quickly over 2 to 3 days. Acute
attacks generally resolve within 5 to 8 days after initiating therapy.
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TREATMENTACUTE GOUTY ARTHRITIS(Fig. 1-1)Nonpharmacologic Therapy• Patients may be advised to reduce their intake of foods high in purines (e.g.,organ meats), avoid alcohol, increase fluid intake, and lose weight if obese.• Joint rest for 1 to 2 days should be encouraged, and local application of icemay be beneficial.Nonsteroidal Antiinflammatory Drugs• Nonsteroidal antiinflammatory drugs (NSAIDs) are the mainstay of therapybecause of their excellent efficacy and minimal toxicity with shorttermuse. There is little evidence to support one NSAID as more efficaciousthan another, and three drugs (indomethacin, naproxen, and sulindac)have FDA approval for this indication (Table 1-1).• Therapy should be initiated with maximum recommended doses for goutat the onset of symptoms and continued for 24 hours after completeresolution of an acute attack, then tapered quickly over 2 to 3 days. Acuteattacks generally resolve within 5 to 8 days after initiating therapy.
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PENGOBATAN
AKUT gout ARTHRITIS
(Gbr. 1-1)
nonfarmakologis Terapi
• Pasien mungkin disarankan untuk mengurangi asupan makanan tinggi purin (misalnya,
daging organ), menghindari alkohol, meningkatkan asupan cairan, dan menurunkan berat badan jika obesitas.
• sisanya Joint selama 1 sampai 2 hari harus didorong, dan aplikasi lokal es
mungkin bermanfaat.
nonsteroid anti peradangan obat
• obat antiinflamasi nonsteroid (NSAID) merupakan andalan terapi
karena khasiat yang sangat baik dan toksisitas minimal dengan jangka pendek
digunakan. Ada sedikit bukti untuk mendukung salah satu NSAID sebagai lebih mujarab
daripada yang lain, dan tiga obat (indometasin, naproxen, dan sulindac)
memiliki persetujuan FDA untuk indikasi ini (Tabel 1-1).
• Terapi harus dimulai dengan maksimal direkomendasikan dosis untuk gout
di timbulnya gejala dan dilanjutkan selama 24 jam setelah selesai
resolusi serangan akut, kemudian meruncing dengan cepat lebih dari 2 sampai 3 hari. Akut
serangan umumnya sembuh dalam 5-8 hari setelah memulai terapi.
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