The essential oils (EOs) of Anthemis melampodina (Am) and Anthemis scrobicularis (As) (Asteraceae) wereextracted from the aerial parts of the plants by hydrodistillation, and their chemical compositions wereanalyzed using GC-FID and GC-MS. Fifty-six components representing 85.5% of the oil composition ofAnthemis melampdina were identified, and the major components were a-pinene (17.1%) andb-eudesmol (13.8%). Forty-one components representing 86% of the oil composition of Anthemis scrobic-ularis were identified, and the major component was b-eudesmol (12.8%). Laboratory bioassays were con-ducted to determine repellency of Am and As EOs against the yellow fever mosquito Aedes aegypti L. andthe lone star tick Amblyomma americanum L. The minimum effective doses (MEDs) of the Am and As EOsagainst mosquitoes were 0.187 ± 0.000 and 0.312 ± 0.063 mg/cm2 respectively, which were significantlyhigher than that of DEET (0.023 ± 0.000 mg/cm2) in human-based repellent bioassays. The As EO wasmore repellent than Am EO against nymphal ticks but was less effective than DEET in vertical paperbioassays.