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Graviola may potentiate antihypertensive and cardiac depressant drugs.63,64It may potentiate antidepressant drugs and interfere with MAO-inhibitor drugs.66,67Co-enzyme Q10 may reduce the activity of graviola. Coenzyme Q10 is required for the functionof the ubiquinone oxidoreductase, which graviola has been shown to inhibit.46,80
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