This study did not show any beneficial effects of lemon juice on elevated BP despite common usage of lemon juice by hypertensive patients, but the study has some limitations. First, the volume of lemon juice was same for the partici- pants, but we were not able to standardize ingredients and determine concentration of ingredients. Although we decided to use a 50 ml dose of lemon juice based on the patients’ statements, the impact of different volumes or concentrations on BP can not be excluded. All of the participants were hy- pertensive, but the level of BP was not so high at the enroll- ment time of the study. More patients are required to reach a reliable conclusion for acute or chronic effect of lemon juice on BP. The study did not evaluate effect of lemon juice on BP among patients having hypertensive urgency or uncontrolled hypertension in conditions which it was used generally, but due to ethical and practical issues to conduct a study for these patients seems to be difficult. Finally, two weeks duration of treatment can be short for final conclusion.