Results (
Thai) 2:
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However, if pregnancy does not
have a “protective” effect on risk of depressive
relapse, somewomenwith a history
of major depression, particularly
those with highly recurrent disease, may
elect to continue taking antidepressants
during pregnancy to avoid the
morbidity associated with depressive relapse.
Similarly, the delineation of time
to relapse has additional clinical importance.
For example, if relapse of major
depression occurs frequently following
antidepressant discontinuation during
pregnancy but is rare in the initial
months following discontinuation, this
serves as a potential clinical guide to
minimize fetal antidepressant exposure
in early pregnancy. Avoiding medications
in the first trimester is consistent
with typical approaches to early
pregnancy.
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