RESULTS
Table 1 shows the type 3 tests of fixed effects. The type 3 tests of hypotheses show differences (P < .0001) in the means of NERL adjusted plasma tCO2 values across time. Differences were also seen (P = .0016) in the means of NERL adjusted plasma tCO2 values ac- cording to furosemide dose. No significant differences
were found (P > .05) in the means of NERL adjusted plasma tCO2 values between weeks. However, a signifi- cant difference was found (P < .0001) according to treatment ϫ hour, suggesting that the change over time was influenced by the dose of furosemide given.