reported the mutant phenotype of loss-of-function pdcd4,
Bam-dependent differentiation of female germline stem cells
may be delayed, leading to an accumulation of pre-cystoblasts in
Drosophila melanogaster. It is possible that Pdcd4 is necessary for
mouse spermatogonial differentiation, which involves the entry
of spermatogonia into meiotic prophase.