This gene encodes a beta chemokine

This gene encodes a beta chemokine receptor, which is
predicted to be a seven transmembrane protein similar to G
protein-coupled receptors. Chemokines and their receptor-mediated
signal transduction are critical for the recruitment of effector
immune cells to the inflammation site. This gene is expressed in a
range of tissues and hemopoietic cells. The expression of this
receptor in lymphatic endothelial cells and overexpression in
vascular tumors suggested its function in chemokine-driven
recirculation of leukocytes and possible chemokine effects on the
development and growth of vascular tumors. This receptor appears to
bind the majority of beta-chemokine family members; however, its
specific function remains unknown. This gene is mapped to
chromosome 3p21.3, a region that includes a cluster of chemokine
receptor genes

Results (Indonesian) 1:

Gen ini encode beta Kemokin reseptor, yang diperkirakan protein transmembran tujuh mirip dengan G reseptor protein-coupled. Chemokines dan mereka reseptor-dimediasi TRANSDUKSI sinyal sangat penting untuk perekrutan efektor sel-sel kekebalan tubuh untuk situs peradangan. Gen ini dinyatakan dalam berbagai jaringan dan sel-sel hemopoietic. Ekspresi ini reseptor ini dalam sel-sel endotel limfatik dan berlebih di tumor vaskular menyarankan fungsinya dalam Kemokin-driven recirculation leukosit meningkat dan mungkin Kemokin efek pada perkembangan dan pertumbuhan tumor vaskular. Reseptor ini tampaknya mengikat sebagian besar anggota keluarga beta-Kemokin; Namun, yang fungsi tertentu masih belum diketahui. Gen ini dipetakan ke 3p21.3 kromosom, sebuah wilayah yang mencakup sekelompok Kemokin gen reseptor