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Despite observational studies that suggest that drinking lowers cardiovascular risk, the possibility of confounding raises concerns about recommending alcohol for heart health.Definitive data from trials are lacking to prove the ardiovascularbenefits of alcohol, and the harms associated with alcohol are well established. S1 and S2 in the Supplementary appendix). For example, beverage alcohol is a carcinogen, and even light drinking is associated with increased risksof oropharyngeal, esophageal, and breast carcinomas.For people with a prior alcohol-use disorder, young adults at low risk for cardiovascular disease, women who are pregnant or trying to conceive, people with conditions that are caused or exacerbated by alcohol in the Supplementary, and people who are going to operate a vehicle or machinery, the risks of drinkingoutweigh any supposed health benefits.
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