Testosteronewasshowntoorganizebrain

Testosteronewasshowntoorganizebrainandmodulatecognitivefunctions.Itiscurrentlyunknown
whether mentalrotationisalsoassociatedwithprenataltestosteroneexposureandtestosterone-related
genetic polymorphisms.Theaimofourstudywastoanalyzeassociationsbetweenmentalrotation
performance, theactualtestosteronelevels,theprenataltestosteronelevel(expressedas2D:4Dratio)
and theandrogenreceptorCAGrepeatpolymorphisminintellectuallygiftedboys.Onehundredforty-
seven boysaged10–18yearswithIQ4130wereenrolled.Salivasampleswerecollectedandusedfor
ELISA ofactuallevelsofsalivarytestosterone.The2D:4D finger lengthratioasanindicatorofprenatal
testosteronewasmeasuredonbothhandsandaveraged.Amthauermentalrotationtestwasusedforthe
assessment ofthisspatialability.TheCAGrepeatpolymorphismintheandrogenreceptorgenewas
analyzed usingPCRandcapillaryelectrophoresis.Linearregressionrevealedthat2D:4D finger length
ratio andthenumberofCAGrepeatsintheandrogenreceptorgenewereassociatedwithmental
rotation.Actuallevelsoftestosteronedidnotcorrelatesignificantly withmentalrotation.Multivariate
analysisofcovariancerevealedthatafteradjustmentofageasaconfoundingvariable,onlytheeffectof
the geneticpolymorphismwassignificant. Theresultsareinlinewithourpreviousgeneticanalysisof
intellectuallygiftedboysshowingtheimportanceofCAGrepeatpolymorphismintheandrogenreceptor
gene. Detailsoftheinteractionsbetweenandrogensignaling,testosteronelevelsanditsmetabolism
especially duringtheprenataldevelopmentofbrainfunctionremaintobeelucidated.

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Testosteronewasshowntoorganizebrainandmodulatecognitivefunctions.Itiscurrentlyunknownли связанные с mentalrotationisalsoassociatedwithprenataltestosteroneexposureandtestosteroneгенетические полиморфизмы. Theaimofourstudywastoanalyzeassociationsbetweenmentalrotationпроизводительность, theactualtestosteronelevels,theprenataltestosteronelevel(expressedas2D:4Dratio)и theandrogenreceptorCAGrepeatpolymorphisminintellectuallygiftedboys.Onehundredforty-семь boysaged10–18yearswithIQ4130wereenrolled.SalivasampleswerecollectedandusedforЭлиза ofactuallevelsofsalivarytestosterone. The2D:4 D палец lengthratioasanindicatorofprenataltestosteronewasmeasuredonbothhandsandaveraged. Amthauermentalrotationtestwasusedfortheоценки ofthisspatialability. TheCAGrepeatpolymorphismintheandrogenreceptorgenewasпроанализированы usingPCRandcapillaryelectrophoresis.Linearregressionrevealedthat2D:4D пальцев длинаКоэффициент andthenumberofCAGrepeatsintheandrogenreceptorgenewereassociatedwithmentalвращение. Actuallevelsoftestosteronedidnotcorrelatesignificantly withmentalrotation. Многовариантное тестированиеanalysisofcovariancerevealedthatafteradjustmentofageasaconfoundingvariable, onlytheeffectofgeneticpolymorphismwassignificant. TheresultsareinlinewithourpreviousgeneticanalysisofintellectuallygiftedboysshowingtheimportanceofCAGrepeatpolymorphismintheandrogenreceptorгена. Detailsoftheinteractionsbetweenandrogensignaling, testosteronelevelsanditsmetabolismособенно duringtheprenataldevelopmentofbrainfunctionremaintobeelucidated.

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Results (Russian) 2:[Copy]

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Testosteronewasshowntoorganizebrainandmodulatecognitivefunctions.Itiscurrentlyunknown
ли mentalrotationisalsoassociatedwithprenataltestosteroneexposureandtestosterone связанных с
генетической polymorphisms.Theaimofourstudywastoanalyzeassociationsbetweenmentalrotation
производительности, theactualtestosteronelevels, theprenataltestosteronelevel (expressedas2D: 4Dratio)
и theandrogenreceptorCAGrepeatpolymorphisminintellectuallygiftedboys.Onehundredforty-
семь boysaged10-18yearswithIQ4130wereenrolled.Salivasampleswerecollectedandusedfor
ELISA ofactuallevelsofsalivarytestosterone.The2D: 4D пальца ofthisspatialability.TheCAGrepeatpolymorphismintheandrogenreceptorgenewas проанализирован usingPCRandcapillaryelectrophoresis.Linearregressionrevealedthat2D: длина 4D пальца соотношение geneticpolymorphismwassignificant. Detailsoftheinteractionsbetweenandrogensignaling, testosteronelevelsanditsmetabolism особенно duringtheprenataldevelopmentofbrainfunctionremaintobeelucidated.

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Results (Russian) 3:[Copy]

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