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Indonesian) 1:
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Streptozotocin injection to adult rats (for simulation oftype 1 diabetes) resulted in severe diabetes, which wascharacterized by hyperglycemia (fasting blood glucoseranging 19.82— 23.22 mmol/L) on the 7th day. In type2 diabetic model rats fasting glucose level was slightlyhigher (6.85— 8.68 mmol/L) indicating the presence offunctioning β-cells. The water extracts and ethanolextracts of M. indica leaves and stem-barks showed noeffect in nondiabetic, type 1 and type 2 diabetic modelrats in the fasting state (Table I). It is seen from theTable 1 that glibenclamide and insulin reduced serumExtracts werefed simultaneouslywith glucoseloadExtractswere fed30 minprior toglucoseAs in normalpostprandialFastingserumglucosePostprandialserumglucoseFastingserumglucosePostprandialserumglucoseFastingserumglucosePostprandialserumglucoseAs in normalpostprandial
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