Given the diversity in the clinical presentation, healthcare
needs, and affected populations, no single surveillance
approach can effectively monitor all blood
disorders. Instead, the selection of an appropriate
method is strongly influenced by several factors, including
diagnosis and screening practices; the acute or
chronic nature of the condition; and the healthcare
utilization pattern, geographic distribution, and social
and cultural norms of the affected population. These
factors pose challenges but also provide strategic opportunities
when choosing and implementing surveillance
methods. This paper discusses the principles, challenges,
and successes experienced in developing and redesigning
CDC-sponsored surveillance of bleeding disorders,
hemoglobinopathies, VTE, and blood safety.