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we degradedit through microwave-assisted process./ After characterization, /we determined that the chitosan had not changed its configuration during the reaction with H2O2 under microwave irradiation. /The inhibitory activity of the degraded chitosan for Newcastle disease was revealed by a hemagglutination test andRT-PCR./ The yield of the beta-chitosan was approximately 30%,/ and its molecular weight can be degraded to 1000 to 10,000 g/mol./ Moreover, the degraded -chitosan has higher antiviral activity,/ reducing the hemagglutination titre to zero,/ compared with alpha-chitosan./ Therefore, beta-chitosan has good development prospects during the development of veterinary drugs for Newcastle disease.
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