In conventional methods targeting at specific EPs, advanced ultra-sensitive instrumental techniques (e.g.GC-
APCI-MS/MS, latest generationLC-MS/MS) have become available but so far they are hardly used for routine
monitoring.The application of such technologies would simplify sample preparation,offer improved possibilities for
simultaneous determination of multiple EPs,and/or significantly improve detection limits for EPs with very low
PNECs.Although higher in costs , the use of such in struments would be highly beneficial for quantitative
determination of prioritized EPs in water , suspended matter,soil and biota.