Ghana depends so much on the export sector for its development . In the context of Vision 2020, the Government expects that total revenue by the year 2020 should be in the region of about US$60 billion, and non-traditional exports alone should be contributing about US$12 billion of the total amount in that year. According to the Hinson and Sorensen (2006), E-business had recognized as a key enabler for the achievement of the Vision 2020 target. This paper considered only the issues pertaining in handicraft sector of the NTEs.