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Clinical practice demonstrates that musculoskeletal andneurological disorders can have a substantial impact on gaitquality. In order to determine the severity of impairment as well asto evaluate therapeutic interventions, the ability of quantifyinggait is of great importance. Objective gait analyses are commonlyachieved by using sophisticated measurement tools such asmarker-based motion analysis systems. However, these systemsare dependent on a laboratory and associated with high costs,restricting their use for most clinical practitioners. Recently,researchers have considered accelerometer-based measurementsystems as a possible alternative to the expensive and timeconsuming laboratory assessments [1,2]. Tri-axial accelerometers,for example, detect changes in velocity in three orthogonal axesand are often used to measure accelerations of a reference pointclose to the body’s centre of mass (CoM).Analysing the motion of the CoM can be used as a simplifiedconcept to look at human locomotion [3]. CoM displacement mightbe seen as the result of all forces acting upon the body[3]. Neurological or musculoskeletal disorders might alter movementsof body segments and thus influence the motion of the CoM[4]. Based on data measured by a motion capture system, previousresearch reported differences in CoM displacement when comparingnormal with pathological gait. Children with myelomeningocele,for instance, showed an increased lateral and vertical CoMdisplacement [5]. Findings of another study investigating gait insubjects with myelomeningocele indicated that vertical CoMdisplacement was related to energy consumption, assessed by the
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