Management of severe and complicate

Management of severe and complicated CDI
14. Supportive care should be delivered to all patients and includes intravenous fluid resuscitation, electrolyte replacement, and pharmacological venous thromboembolism prophylaxis. Furthermore, in the absence of ileus or signifi cant abdominal distention, oral or enteral feeding should be continued. (Conditional recommendation, low-quality evidence)
15. CT scanning of the abdomen and pelvis is recommended in patients with complicated CDI. (Conditional recommendation, low-quality evidence)
16. Vancomycin delivered orally (125 mg four times per day) plus intravenous metronidazole (500 mg three times a day) is the treatment of choice in patients with severe and complicated CDI who have no signifi cant abdominal distention. (Strong recommendation, low-quality evidence)
17. Vancomycin delivered orally (500 mg four times per day) and per rectum (500 mg in a volume of 500 ml four times a day) plus intravenous metronidazole (500 mg three times a day) is the treatment of choice for patients with complicated CDI with ileus or toxic colon and / or signifi cant abdominal distention. (Strong recommendation, low-quality evidence)
18. Surgical consult should be obtained in all patients with complicated CDI. Surgical therapy should be considered in patients with any one of the following attributed to CDI: hypotension requiring vasopressor therapy; clinical signs of sepsis and organ dysfunction (renal and pulmonary); mental status changes; white blood cell count ≥ 50,000 cells / μ l, lactate ≥ 5 mmol / l; or failure to improve on medical therapy after 5 days. (Strong recommendation,
moderate-quality evidence)

Results (Indonesian) 1:

Management of severe and complicated CDI14. Supportive care should be delivered to all patients and includes intravenous fluid resuscitation, electrolyte replacement, and pharmacological venous thromboembolism prophylaxis. Furthermore, in the absence of ileus or signifi cant abdominal distention, oral or enteral feeding should be continued. (Conditional recommendation, low-quality evidence)15. CT scanning of the abdomen and pelvis is recommended in patients with complicated CDI. (Conditional recommendation, low-quality evidence)16. Vancomycin delivered orally (125 mg four times per day) plus intravenous metronidazole (500 mg three times a day) is the treatment of choice in patients with severe and complicated CDI who have no signifi cant abdominal distention. (Strong recommendation, low-quality evidence)17. Vancomycin delivered orally (500 mg four times per day) and per rectum (500 mg in a volume of 500 ml four times a day) plus intravenous metronidazole (500 mg three times a day) is the treatment of choice for patients with complicated CDI with ileus or toxic colon and / or signifi cant abdominal distention. (Strong recommendation, low-quality evidence)18. bedah berkonsultasi harus diperoleh pada semua pasien dengan CDI rumit. Terapi bedah harus dipertimbangkan dalam pasien dengan salah satu dari berikut dikaitkan dengan CDI: hipotensi memerlukan terapi vasopressor; tanda-tanda klinis disfungsi sepsis dan organ (ginjal dan paru-paru); perubahan mental status; sel darah putih count ≥ 50.000 sel / μ l, laktat ≥ 5 mmol / l; atau kegagalan untuk memperbaiki terapi medis setelah 5 hari. (Rekomendasi kuat,bukti kualitas moderat)