Immobilization of whole cells has become an important toolin biotechnology. The process involves attachment of cells in thedistinct solid phase which permits exchange of substrates, prod-ucts and inhibitors but at the same time separates catalytic cellbiomass from the liquid phase containing substrates and products.Immobilization offers the possibility of reuse of cells and their sim-ple separation from the fermentation broth, as well as facilitatingisolation and purification of products and reducing the costs ofbioprocesses [12]. Moreover, immobilization often improves theoperational and storage stability of the enzymes present in immo-bilized whole cells. It is also facilitating continuous operation overa prolonged period [13]. There are a wide variety of immobilizationcarriers that has been reported and among them polyurethane foamis particularly convenient for use in bioprocesses due to its chem-ical stability and mechanical plasticity. Polyurethane foam hasbeen used for the immobilization of many fungal strains produc-ing microbial secondary metabolites [14] including glucose oxidase[15] and pectinase [16].