we degraded
it through microwave-assisted process.
/ After characterization,
/we determined that the chitosan had not changed its configuration during the reaction with H2O2 under microwave irradiation.
/The inhibitory activity of the degraded chitosan for Newcastle disease was revealed by a hemagglutination test and
RT-PCR.
/ The yield of the beta-chitosan was approximately 30%,
/ and its molecular weight can be degraded to 1000 to 10,000 g/mol.
/ Moreover, the degraded -chitosan has higher antiviral activity,
/ reducing the hemagglutination titre to zero,
/ compared with alpha-chitosan.
/ Therefore, beta-chitosan has good development prospects during the development of veterinary drugs for Newcastle disease.