Conventional drugs commonly used in acne treatment – such as tetracycline, erythromycin, mynocycline and metronidazole topical agent for the treatment of acne. These drugs also have various known side effects. The topical antibiotics can lead to dryness, redness and irritation of the skin, as well as hypopigmentation while oral antibiotics have age restrictions can cause gastrointestinal disorders and increase the risk of venous thromboembolism