It was supposed that polycationic s

It was supposed that polycationic structure of chitosan in acidic media could interact
with anionic components (i.e., proteins, phospholipids) of cell surface, thereby
interfering their normal growth and metabolism (Fang, Li & Dyc, 1994; Shahidi,
Arachchi & Jeon, 1999; Roller & Covill, 1999; Bautista-Baños et al, 2006). Another
possible mechanism is that chitosan chains may cross the cell membrane, interact with
DNA, alter its conformation, leading to inhibition of the synthesis of mRNA and
proteins (Sajomsang, Gonil, Saesoo & Ovatlarnporn, 2012; Tan, Rui, Lin, Liu & Tang,
2013).It is possible that the water-soluble SCS is able to penetrate cell walls and
membranes interfering directly with the activity of enzymes responsible for growth of
the fungi.
Abnormal shapes and swelling mycelia of pyridine chitosan-treated B. cinerea
observed from SEM (Jia, Duan, Fang, Wang & Huang, 2016) were similar with the
WCS-treated A. sacchari, but significantly different from the SCS-treated A. sacchari.
4. Conclusion

Results (Indonesian) 2:

Itu seharusnya bahwa struktur polikationik chitosan dalam media asam bisa berinteraksi
dengan komponen anionik (yaitu, protein, fosfolipid) dari permukaan sel, sehingga
mengganggu pertumbuhan normal dan metabolisme (Fang, Li & DYC, 1994; Shahidi,
Arachchi & Jeon 1999 ; Roller & Covill, 1999; Bautista-Baños et al, 2006). Lain
mekanisme yang mungkin adalah bahwa rantai chitosan dapat melintasi membran sel, berinteraksi dengan
DNA, mengubah konformasi, menyebabkan penghambatan sintesis mRNA dan
protein (Sajomsang, Gonil, Saesoo & Ovatlarnporn, 2012; Tan, Rui, Lin, Liu & tang,
2013) .Hal ini mungkin bahwa SCS larut dalam air mampu menembus dinding sel dan
membran campur langsung dengan aktivitas enzim yang bertanggung jawab untuk pertumbuhan
jamur.
bentuk abnormal dan pembengkakan miselia piridin kitosan-diperlakukan B. cinerea
diamati dari SEM (Jia, Duan, Fang, Wang & Huang, 2016) adalah serupa dengan
A. sacchari WCS-diobati, tetapi berbeda secara signifikan dari A. sacchari SCS-diobati.
4. Kesimpulan