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The hemoglobin-haptoglobin scavenger receptor(CD163) is a monocyte/macrophage-restricted transmembraneprotein of the cysteine-rich scavenger receptorfamily. CD163 expression identifies macrophagesundergoing the alternative pathway of differentiationthat is associated with enhanced phagocytic activity .The extracellular portion of CD163 is shed from the cellsurface in the form of sCD163 when cells are appropriatelyactivated.
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