Sorption calorimetry is less commonly used in routine characterization
of drug substances and raw materials. In contrast,
automated water sorption equipment is a standard technique
that requires minimal sample preparation and effort,making it
more appropriate for routine characterization. The main data
obtained by the water sorption technique is water weight versus
RH. Although it is necessary to quantify the water content
of materials and the isotherm provides practical value in characterizing
their “hygroscopicity