196 J. Ozer et al. / Toxicology 245

196 J. Ozer et al. / Toxicology 245 (2008) 194–205Table 1The abbreviations used are for standard hepatotoxicity assays: alanine aminotransferase activity (ALT), alanine aminotransferase isoform 1 (ALT1), alanine aminotransferase isoform 2 (ALT2),aspartate aminotransferase activity (AST), alkaline phosphatase activity (ALP), gamma-glutamyl transferase activity (GGT); for enzymatic hepatotoxicity assays: sorbitol dehydrogenase activity(SDH), glutamate dehydrogenase activity (GLDH), malate dehydrogenase activity (MDH), purine nucleoside phosphorlyase activity (PNP), paraoxonase-1 activity (PON1); and for ELISA (EIA)hepatotoxicity assays: hydroxyphenylpyruvate dioxygenase (HPD) and glutathione-S-transferase ␣ (GST␣). Amino acid (aa) is indicated in biological activity

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196 J. Ozer et al. / 245 Toksikologi (2008) 194-205Table 1 singkatan yang digunakan untuk tes standar hepatotoksisitas: alanin aminotransferase aktivitas (ALT), alanin aminotransferase isoform 1 (ALT1), alanin aminotransferase isoform 2 (ALT2), Aspartat aminotransferase aktivitas (AST), alkali fosfatase aktivitas (ALP), gamma-glutamil transferase aktivitas (GGT); untuk tes enzimatik hepatotoksisitas: sorbitol dehidrogenase activity(SDH), glutamat dehidrogenase aktivitas (GLDH), malate dehidrogenase aktivitas (MDH), purina nukleosida phosphorlyase kegiatan (PNP), paraoxonase-1 aktivitas (PON1); dan untuk tes hepatotoksisitas ELISA (EIA): hydroxyphenylpyruvate dioxygenase (HPD) dan glutathione-S-transferase ␣ (GST␣). Asam amino (aa) diindikasikan dalam aktivitas biologis

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196 J. Ozer et al. / Toksikologi 245 (2008) singkatan 194-205Table 1The digunakan adalah untuk tes hepatotoksisitas standar: aktivitas SGPT (ALT), SGPT isoform 1 (ALT1), SGPT isoform 2 (ALT2), aktivitas aminotransferase aspartat (AST), fosfatase alkali kegiatan (ALP), gamma-glutamyl aktivitas transferase (GGT); untuk enzimatik tes hepatotoksisitas: aktivitas dehidrogenase sorbitol (SDH), aktivitas glutamat dehidrogenase (GLDH), aktivitas dehidrogenase malat (MDH), purin nukleosida aktivitas phosphorlyase (PNP), paraoxonase-1 kegiatan (PON1); dan untuk ELISA (EIA) tes hepatotoksisitas: hydroxyphenylpyruvate dioksigenase (HPD) dan glutathione-S-transferase ␣ (GST␣). Asam amino (aa) ditunjukkan dalam aktivitas biologis

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