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The analysis of DNA methylation-based biomarkers is a rapidly advancing area of research, being actively studied in multiple cancers, with the possibility of the methylation profile to distinguish tumour types and perhaps the response to chemotherapeutic agents. Already, tumour-specific DNA methylation patterns can be detected in tumour-derived free circulating DNA from the bloodstream of cancer patients, coming from DNA, derived from the primary tumour source of the patient. Therefore, the need for detection of aberrancies of DNA methylation appears to be one of the most important assays in early cancer diagnosis.
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