some medications may lessen the myotonia, nothing improves the weakness. The abnormality adversely affects gene function in other organs, causing other trinucleotide somatic features in myotonic dystrophy type l patients, such as cataracts, frontal Although no curative treatment currently baldness, infertility, and cardiac arrhythmias. exists, a cardiac pacemaker may be life-preserving in patients with heart block. Mitochondrial myopathies are hereditary disorders with abnormalities of various mitochondrial enzymes, often affecting the brain in addition to muscle.