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From the above results, we concluded that dietary supplementwith 1% CGMP significantly alleviated the decrease in growth performancecaused by E. coli infection. The beneficial effects of CGMPmay rely on the inhibition of pathogen overgrowth and specificadhesion to K88 strain, which prevented intestinal morphologyfrom being damaged, inhibited the increase of intestinal permeability,and avoided the inflammatory responses induced by pathogeninvasion. These results suggested that CGMP might be used todevelop an effective feed additive to protect the weaning pigletsfrom PWD.
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