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The pericardium is rarely the primary site of infection,but is more often secondarily infected either by hematogenousspread, direct spread from adjacent structures, orafter cardiac surgery. With the availability of broadspectrumantibiotics, the incidence has decreased, whilethe etiologic agents have changed from predominantlypneumococcus and streptococcal species to staphylococcus,anaerobes, and fungus, especially in an immunocompromisedhost.
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