In terms of clinical pain, a recent systematic review andmeta-analysis of cannabinoids for medical use that examined 28 randomized trials among 2454 patients withchronic pain indicated that, compared with placebo, cannabinoids were associated with greater a reduction in pain(37% vs. 31%; OR 1.41, 95% CI 0.99 to 2.00) and greateraverage reduction in numerical pain ratings (0.46, 95%CI0.80 to0.11).73 Whiting et al. concluded that therewas moderate evidence to support the use of cannabinoids for the treatment of chronic pain. In this review,Hill, et al.; Cannabis and Cannabinoid Research 2017, 2.1http://online.liebertpub.com/doi/10.1089/can.2017.0017100neuropathy was the most commonly cited source ofchronic pain. The majority of studies focused on testingthe effects of plant-derived cannabinoids. Only 5 of the28 trials assessed the effects of vaporized or smoked cannabis plant flower. Of note, cannabinoids were associatedwith an increased risk for short-term adverse events, including serious adverse events, compared to placebo
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In terms of clinical pain, a recent systematic review and<br>meta-analysis of cannabinoids for medical use that examined 28 randomized trials among 2454 patients with<br>chronic pain indicated that, compared with placebo, cannabinoids were associated with greater a reduction in pain<br>(37% vs. 31%; OR 1.41, 95% CI 0.99 to 2.00) and greater<br>average reduction in numerical pain ratings (0.46, 95%<br>CI0.80 to0.11).73 Whiting et al. concluded that there<br>was moderate evidence to support the use of cannabinoids for the treatment of chronic pain. In this review,<br>Hill, et al.; Cannabis and Cannabinoid Research 2017, 2.1<br>http://online.liebertpub.com/doi/10.1089/can.2017.0017<br>100<br>neuropathy was the most commonly cited source of<br>อาการปวดเรื้อรัง ส่วนใหญ่ของการศึกษามุ่งเน้นไปที่การทดสอบ<br>ผลกระทบของ cannabinoids พืชที่ได้รับ เพียง 5 ของ<br>28 การทดลองประเมินผลกระทบของดอกไม้พืชระเหยหรือรมควันกัญชา โน้ต cannabinoids มีความสัมพันธ์<br>กับความเสี่ยงที่เพิ่มขึ้นสำหรับเหตุการณ์ไม่พึงประสงค์ในระยะสั้นรวมทั้งเหตุการณ์ไม่พึงประสงค์ที่รุนแรงเมื่อเทียบกับยาหลอก
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