Differential Diagnosis: Considerations may be neoplasms lipomas, vascular malformations, a dermoid cyst (when in the floor of the mouth), as well as mucoepidermoid carcinoma in the palate region. Sometimes, the clinical and microscopic features may be mistaken for other condi tions such as pemphigoid, bullous lichen planus, papilloma. fibroma, or current HSV infections Treatment and Prognosis: When a mucocele is classified as a mucous cyst or blockage of the duct,surgical approaches are warranted. These approaches are discussed in Chapter 17 under salivary gland diseases and may include surgery with marsupialization and laser ablation.