Many studies have showed that the risk of cardiovascular disease and a translation - Many studies have showed that the risk of cardiovascular disease and a Indonesian how to say

Many studies have showed that the r

Many studies have showed that the risk of cardio
vascular disease and atherosclerosis is closely related to
high level of cholesterol in the blood which may caused
increased in low-density lipoprotein (LDL) in circulating
blood and get deposited in the vascular system to form
atherosclerosis (Diaz et al. 1997). The elevation of
LDL is easily attacked by natural occurring free radical
in body into oxidized form of LDL (De Groot & Noll
1987). Gutteridge (1989) showed that free radicals play
an important role in the development of tissue damage
and pathological events. The conformational changes
of lipoprotein of oxidized LDL will lead to deposition in
blood vessel of aorta. Thus, antioxidant plays a significant
role by delaying or reducing the oxidation of LDL and be
able to prevent the formation of atherosclerosis.
Rhodomyrtus tomentosa or commonly known as
Kemunting by the Malays in Malaysia is a large evergreen
shrub native originated from South East Asia (Verheij &
Coronel 1992). It belongs to the family of Myrtaceae and
is an evergreen shrub native to South East Asia (Latiff
1992). It has been used as one of the components in
traditional medicines to treat urinary tract infections (Wei
2006). The blueberry-like fruit are edible and contains
sugars, vitamins and minerals. The roots and leaves
were used to treat diarrhoea, wounds, stomach aches
and as a tonic after childbirth. The fruits have the effect
on reducing cholesterol level and it has antioxidative
effect due to rich in chemical compounds (Asadhawut
& Wilawan 2008; Crow et al. 1971; Dachriyanus et
al. 2004). There are many cholesterol lowering effect
of dietary plants which has been studied from plants
(Hamendra & Anand 2007; Shela et al. 2003). However,
there are no studies on the antioxidant activities have been
reported in Rhodomyrtus tomentosa fruits. In this study,
antioxidant activities of Rhodomyrtus tomentosa and
its effect is investigated on the lipid profile in inducedcholesterol
New Zealand White rabbits.
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Many studies have showed that the risk of cardiovascular disease and atherosclerosis is closely related tohigh level of cholesterol in the blood which may causedincreased in low-density lipoprotein (LDL) in circulatingblood and get deposited in the vascular system to formatherosclerosis (Diaz et al. 1997). The elevation ofLDL is easily attacked by natural occurring free radicalin body into oxidized form of LDL (De Groot & Noll1987). Gutteridge (1989) showed that free radicals playan important role in the development of tissue damageand pathological events. The conformational changesof lipoprotein of oxidized LDL will lead to deposition inblood vessel of aorta. Thus, antioxidant plays a significantrole by delaying or reducing the oxidation of LDL and beable to prevent the formation of atherosclerosis.Rhodomyrtus tomentosa or commonly known asKemunting by the Malays in Malaysia is a large evergreenshrub native originated from South East Asia (Verheij &Coronel 1992). It belongs to the family of Myrtaceae andis an evergreen shrub native to South East Asia (Latiff1992). It has been used as one of the components intraditional medicines to treat urinary tract infections (Wei2006). The blueberry-like fruit are edible and containssugars, vitamins and minerals. The roots and leaveswere used to treat diarrhoea, wounds, stomach achesand as a tonic after childbirth. The fruits have the effecton reducing cholesterol level and it has antioxidativeeffect due to rich in chemical compounds (Asadhawut& Wilawan 2008; Crow et al. 1971; Dachriyanus etal. 2004). There are many cholesterol lowering effectof dietary plants which has been studied from plants(Hamendra & Anand 2007; Shela et al. 2003). However,there are no studies on the antioxidant activities have beenreported in Rhodomyrtus tomentosa fruits. In this study,antioxidant activities of Rhodomyrtus tomentosa andits effect is investigated on the lipid profile in inducedcholesterolNew Zealand White rabbits.
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Banyak penelitian telah menunjukkan bahwa risiko cardio
penyakit pembuluh darah dan aterosklerosis berkaitan erat dengan
tingkat tinggi kolesterol dalam darah yang dapat menyebabkan
peningkatan di low-density lipoprotein (LDL) dalam sirkulasi
darah dan bisa disimpan dalam sistem vaskular untuk membentuk
aterosklerosis ( Diaz et al. 1997). Ketinggian
LDL mudah diserang oleh terjadi alami radikal bebas
dalam tubuh menjadi bentuk teroksidasi dari LDL (De Groot & Noll
1987). Gutteridge (1989) menunjukkan bahwa radikal bebas memainkan
peran penting dalam pengembangan kerusakan jaringan
dan acara patologis. Perubahan konformasi
dari lipoprotein LDL teroksidasi akan menyebabkan pengendapan di
pembuluh darah aorta. Dengan demikian, antioksidan memainkan signifikan
peran dengan menunda atau mengurangi oksidasi LDL dan menjadi
mampu mencegah pembentukan aterosklerosis.
Kemunting atau yang biasa dikenal sebagai
Kemunting oleh orang Melayu di Malaysia adalah cemara besar
semak asli berasal dari Asia Tenggara (Verheij &
Coronel 1992). Ini milik keluarga Myrtaceae dan
merupakan semak asli cemara ke Asia Tenggara (Latiff
1992). Telah digunakan sebagai salah satu komponen dalam
obat-obatan tradisional untuk mengobati infeksi saluran kemih (Wei
2006). Buah blueberry-seperti yang dimakan dan mengandung
gula, vitamin dan mineral. Akar dan daun
digunakan untuk mengobati diare, luka, sakit perut
dan sebagai tonik setelah melahirkan. Buah memiliki efek
pada pengurangan tingkat kolesterol dan memiliki antioksidan
efek karena kaya akan senyawa kimia (Asadhawut
& Wilawan 2008; Gagak et al 1971;. Dachriyanus et
al 2004.). Ada banyak menurunkan kolesterol efek
dari tanaman makanan yang telah dipelajari dari tanaman
(Hamendra & Anand 2007; Shela et al 2003.). Namun,
tidak ada studi tentang kegiatan antioksidan telah
dilaporkan dalam buah-buahan kemunting. Dalam studi ini,
aktivitas antioksidan dari kemunting dan
efeknya diselidiki pada profil lipid di inducedcholesterol
Selandia Baru White kelinci.
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