Compared to those seeded on PLA and PHB, rabbit bone marrow cells inoculated on three-dimensional PHBHHx scaffolds show more differentiation into osteoblast-like cells, with a round cell shape, high alkaline phosphatase activity, strong calcium deposition, and fibrillar collagen synthesis.
This finding suggests that PHBHHx is a suitable biomaterial for promotion of osteoblast attachment, proliferation, and
differentiation