5-Nitroimidazoles•Wide-spectrum•Met

5-Nitroimidazoles
•Wide-spectrum
•Metronidazole–against anaerobic bacteria and protozoan infections.
•Tinidazole–longer duration of action.
•Diffuses into the organism where the nitro group is reduced chemically reactive intermediates are formed that inhibit DNA synthesis and/or damage DNA.

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5-Nitroimidazoles•Wide-spectrum•Metronidazole–against anaerobic bacteria and protozoan infections.•Tinidazole–longer duration of action.•Diffuses into the organism where the nitro group is reduced chemically reactive intermediates are formed that inhibit DNA synthesis and/or damage DNA.

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5-Nitroimidazoles
• Wide-spektrum
• Metronidazole-terhadap bakteri anaerob dan infeksi protozoa.
• Tinidazol-lagi durasi kerja.
• berdifusi ke organisme di mana kelompok nitro berkurang chemically intermediet reaktif terbentuk yang menghambat sintesis DNA dan / atau kerusakan DNA.

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