CONCLUSIONS
Our study is the largest postlicensure
population-based study to date to examine
the association between seizures
and DTaP. Among children aged
6 weeks to 23 months, no increased
risk for seizures in the 0 to 3 days after
DTaP vaccination was observed. Safety
concerns about DTP resulted in declining
public trust in vaccines, which affected
the immunization programs.5,6
The use of DTaP has replaced the use of
DTP in the United States.13 Our findings
provide reassuring evidence that the
vaccine is not associated with acute
seizure events and is safe for routine
immunization in early childhood.