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5.9 Glucocorticoids for pain managementGlucocorticoids have a number of beneficial properties in a surgical setting. In addition tobeing antiemetic, they are antiinflammatory, analgesic, antipyretic, and antiallergic34.Glucocorticoids exert their effects by binding to a glucocorticoid receptor (GR) localized inthe cytoplasm of target cells. There is a single class of GR that binds glucocorticoids, with noevidence for subtypes of differing affinity in different tissues35.
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