The diagnosis of TM is suspected when there are acute or subacute signs and symptoms of
motor, sensory, and/or autonomic dysfunction that localize to one or more contiguous spinal cord segments in
patients with no evidence of a compressive cord lesion. Thus, the diagnosis of TM requires exclusion of a
compressive cord lesion, usually by MRI, and confirmation of inflammation by either gadolinium-enhanced MRI
or lumbar puncture.