The production of second-generation biofuels from lignocellulose-based raw materials that are derived from agricultural, forest and municipal solid wastes can provide strategic, economic and environmental benefits (1). The increasing demand for food, feed, and energy has raised several concerns about the potential use of food-based biofuels and their future sustainability. Moreover, global warming and energy security concerns have intensified the search for safe and effective methods to commercially produce bioethanol from cellulose-based biomass. Bioethanol is completely renewable in nature with zero net carbon emissions (2). Microbial fermentation offers a promising alternative for the production of sustainable biofuels. Recently, Saccharomyces cerevisiae has received much attention as a vehicle for the production of ethanol and higher alcohols (3).